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# MetagenomicsBench results

> Agentic microbial community analysis tasks spanning shotgun, amplicon, long-read and spatially integrated metagenomics.

Data updated: 2026-09-29

Artifact generated: 2026-09-29T18:01:39.911Z

- Domain: Omics
- Horizon: short
- Assessment: Capabilities
- Published score scope: Full benchmark (100 evaluations)

Scores use a 0–100 percentage scale. Consult the repository and paper for benchmark-specific task construction, grading, aggregation, and uncertainty methodology. Results compare model-and-harness combinations.

| Rank | Model | Harness | Provider | Score |
| ---: | --- | --- | --- | ---: |
| 1 | Claude Opus 5 | Pi | Anthropic | 54.0% |
| 2 | Claude Opus 5 | Claude Code | Anthropic | 53.3% |
| 3 | Claude Opus 4.8 | Claude Code | Anthropic | 50.0% |
| 4 | GPT-6 Astra | Codex | OpenAI | 49.7% |
| 5 | Claude Opus 4.8 | Pi | Anthropic | 48.3% |
| 6 | GPT-6 Astra | Pi | OpenAI | 47.0% |
| 7 | Claude Sonnet 5 | Pi | Anthropic | 42.3% |
| 8 | Grok 4.6 | Grok Build | SpaceXAI | 42.0% |
| 9 | Claude Sonnet 5 | Claude Code | Anthropic | 41.0% |
| 10 | Grok 4.6 | Pi | SpaceXAI | 38.7% |
| 11 | DeepSeek V4.1 Flash | Pi | DeepSeek | 38.0% |
| 12 | Claude Opus 4.7 | Pi | Anthropic | 35.3% |
| 13 | GPT-5.6 Sol | Pi | OpenAI | 31.3% |
| 14 | GPT-5.6 Sol | Codex | OpenAI | 28.7% |
| 15 | Kimi K3 | Pi | Moonshot | 27.3% |
| 16 | GPT-5.6 Luna | Codex | OpenAI | 24.3% |
| 17 | GPT-5.6 Luna | Pi | OpenAI | 22.7% |

## Sources and downloads

- [Paper PDF](/papers/metagenomics.pdf)
- [Original publication](https://latch.bio/metagenomicsbench)
- [Repository](https://github.com/latchbio/metagenomicsbench)
- [Interactive benchmark](https://benchmarks.bio/metagenomics)
- [JSON](https://benchmarks.bio/benchmarks/metagenomics/latest.json)
- [CSV](https://benchmarks.bio/benchmarks/metagenomics/latest.csv)
- [V1 cross-benchmark leaderboard](https://benchmarks.bio/results/v1/)
